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Invitrogen™ MST3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5120097
Description
Positive test controls include: HeLa, A375, U-251MG, HT-29, NIH/3T3, Mouse liver, Mouse kidney, Mouse lung, Rat liver. The target is usually found in the following locations: Cytoplasm, Membrane, Nucleus. Immunogen sequence: TDGQASGGSD SGDWIFTIRE KDPKNLENGA LQPSDLDRNK MKDIPKRPFS QCLSTIISPL FAELKEKSQA CGGNLGSIEE LRGAIYLAEE ACPGISDTMV AQLVQRLQRY SLSGGGTSSH.
STK24 (MST3) is a serine/threonine kinase that is a member of the GCK subfamily of STE20-like proteins. The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases.
Specifications
MST3 | |
Polyclonal | |
Unconjugated | |
STK24 | |
1810013H02Rik; C76483; epididymis secretory protein Li 95; HEL-S-95; Mammalian STE20-like protein kinase 3; Mammalian STE20-like protein kinase 3 C-terminal; Mammalian STE20-like protein kinase 3 N-terminal; mammalian sterile twenty 3 kinase; Mst3; MST-3; MST3/C; MST3/N; MST3B; OTTHUMP00000018594; RGD1561742; RP11-111L24.5; serine/threonine kinase 24; serine/threonine kinase 24 (STE20 homolog, yeast); serine/threonine-protein kinase 24; Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase 24 35 kDa subunit; Serine/threonine-protein kinase 24 36 kDa subunit; STE20; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK24; STK3 | |
Rabbit | |
Affinity chromatography | |
RUO | |
223255, 361092, 8428 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
2.55 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
B0LT89, Q99KH8, Q9Y6E0 | |
STK24 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 312-431 of human STK24 (NP_001027467.2). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
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