Invitrogen™ MST4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521866

Catalog No. PIPA521866

Description

Recommended positive controls: A549, IMR32. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MST4 is member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: MST4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Stk26
• Gene Alias: 2610018G03Rik; Mammalian STE20-like protein kinase 4; mammalian sterile 20-like 4; Mask; Mst3 and SOK1-related kinase; Mst4; MST-4; OTTHUMP00000215132; OTTHUMP00000215134; RGD1563568; RP6-213H19.1; serine/threonine kinase 26; serine/threonine protein kinase 26; serine/threonine protein kinase MST4; serine/threonine-protein kinase 26; Serine/threonine-protein kinase MASK; serine/threonine-protein kinase MST4; STE20-like kinase 4; STE20-like kinase MST4; STK26
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51765
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9P289
• Gene Symbols: Stk26
• Immunogen: Synthetic peptide corresponding to a region within amino acids 352 and 416 of MST4 (Uniprot ID#Q9P289).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov