Invitrogen™ MSX1/MSX2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103302

Catalog No. PIPA5103302

Description

Antibody detects endogenous levels of total MSX1/2.

Drosophila,muscle segment (msh) homolog 1,homeo domain encoding gene,inhibiting MYOD1 expression,highly expressed in dental mesenchyme during critical bud stage,involved in epithelial-mesenchymal signaling in many organs,and in the pathogenesis of cleft lip and palate,interacting with MSX2 in mouse limb bud patterning .This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition.Tissue specificity: Expressed in the developing nail bed mesenchyme.

Specifications

• Antigen: MSX1/MSX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MSX1
• Gene Alias: AA675338; AI324650; BB122635; CRS2; ECTD3; FPP; homeo box, msh-like 1; homeo box, msh-like 2; homeobox 7; homeobox protein Hox-7; Homeobox protein Hox-8; homeobox protein Hox-8-1; Homeobox protein MSX-1; homeobox protein MSX-2; homeobox, msh-like 1; homeobox, msh-like 2; Hox7; Hox-7; Hox7.1; Hox-7.1; HOX8; Hox-8; Hox8.1; Hox-8.1; HYD1; msh; msh homeo box 1; msh homeo box 2; msh homeo box homolog 2; msh homeobox 1; msh homeobox 1-like protein; msh homeobox 2; msh homeobox homolog 1; msh homeobox homolog 2; Msx1; MSX2; Msx-2; muscle-segment homeobox; PFM; PFM1; STHAG1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17701, 17702, 25483, 4487, 4488, 81710
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P13297, P28360, P35548, P52953, Q03358
• Gene Symbols: MSX1, MSX2
• Immunogen: A synthesized peptide derived from human MSX1(Accession P28360), corresponding to amino acid residues W145-Q195.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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