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Invitrogen™ MT-ND2 Polyclonal Antibody
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Catalog No. PIPA5120600
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100 μL
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PIPA5120600 100 μL
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Catalog No. PIPA5120600 Supplier Invitrogen™ Supplier No. PA5120600
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse brain, Rat brain. Immunogen sequence: LLSLGGLPPL TGFLPKWAII EEFTKNNSLI IPTIMATITL LNLYFYLRLI YSTSITLLPM SNNVKMKWQF EHTKPTPFLP TLIALTTLLL PISPFMLMIL.

MT-ND2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND2 are a cause of Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. Defects in MT-ND2 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT).
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Specifications

Antigen MT-ND2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene MT-ND2
Gene Accession No. P03891, P03893, P11662
Gene Alias mitochondrially encoded NADH dehydrogenase 2; Mtnd2; mt-Nd2; NADH dehydrogenase subunit 2; NADH2; NADH-ubiquinone oxidoreductase chain 2; ND2
Gene Symbols MT-ND2, ND2
Host Species Rabbit
Immunogen Synthetic Peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17717, 26194, 4536
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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