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Invitrogen™ MT-ND2 Polyclonal Antibody
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Catalog No. PIPA537185
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100 μL
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Catalog No. Quantity
PIPA537185 100 μL
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Catalog No. PIPA537185 Supplier Invitrogen™ Supplier No. PA537185
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 39 kDa. Purity is >95% by SDS-PAGE.

MT-ND2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND2 are a cause of Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. Defects in MT-ND2 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MT-ND2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene MT-ND2
Gene Accession No. P03891, P03893, P11662
Gene Alias mitochondrially encoded NADH dehydrogenase 2; Mtnd2; mt-Nd2; NADH dehydrogenase subunit 2; NADH2; NADH-ubiquinone oxidoreductase chain 2; ND2
Gene Symbols MT-ND2, ND2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues in human MT-ND2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17717, 26194, 4536
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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