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Invitrogen™ MT-ND3 Polyclonal Antibody
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Catalog No. PIPA5103274
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100 μL
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PIPA5103274 100 μL
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Catalog No. PIPA5103274 Supplier Invitrogen™ Supplier No. PA5103274
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MT-ND3.

NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.
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Specifications

Antigen MT-ND3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MT-ND3
Gene Accession No. P03897, P03899, P05506
Gene Alias 1.6.5.3; mitochondrially encoded NADH dehydrogenase 3; Mtnd3; mt-Nd3; NADH dehydrogenase subunit 3; NADH3; NADH-ubiquinone oxidoreductase chain 3; ND3
Gene Symbols MT-ND3
Host Species Rabbit
Immunogen A synthesized peptide derived from human MT-ND3(Accession P03897), corresponding to amino acid residues L15-F65.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17718, 26199, 4537
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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