Invitrogen™ MT-ND4L Polyclonal Antibody

Catalog No.	Quantity
PIPA568242	100 μL

Catalog No. PIPA568242 Supplier Invitrogen™ Supplier No. PA568242

Description

Rabbit Polyclonal Antibody

MT-ND4L Polyclonal Antibody for Western Blot

NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 4L (ND4L) is most likely a component of the hydrophobic protein fragment of Complex I. Mutations in the gene encodiing for ND4 are implicated in Leber hereditary optic neuropathy, a rare condition that can cause loss of central vision.

Specifications

• Antigen: MT-ND4L
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: MT-ND4L
• Gene Accession No.: P03901
• Gene Alias: mitochondrially encoded NADH 4L dehydrogenase; MTND4L; mt-Nd4l; NADH dehydrogenase subunit 4L; NADH4L; NADH-ubiquinone oxidoreductase chain 4L; Nd4l
• Gene Symbols: MT-ND4L
• Host Species: Rabbit
• Immunogen: Synthesized peptide derived from human MT-ND4L.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4539
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov