Invitrogen™ MT-ND5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588563

Catalog No. PIPA588563

Description

Immunogen sequence: KIIAFSTSSQ LGLMMVTLGM NQPHLAFLHI CTHAFFKAML FMCSGSIIHS LADEQDIRKM GNITKIMPFT SSCLVIGSLA LTGMPFLTGF YSKDLIIEAI N; Positive Samples: U-251MG, HeLa, Mouse heart, Rat heart; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein.

A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 5 (ND5) is most likely a component of the hydrophobic protein fragment of Complex I. Mutations in the gene encoding for ND5 are implicated in Mitochondrial neurogastrointestinal encephalomyopathy, an autosomal recessive multisystem disorder that results in dramatically elevated levels of circulating thymidine and deoxyuridine.

Specifications

• Antigen: MT-ND5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MT-ND5
• Gene Alias: mitochondrially encoded NADH dehydrogenase 5; MTND5; mt-Nd5; NADH Dehydrogenase 5; NADH dehydrogenase subunit 5; NADH5; NADH-ubiquinone oxidoreductase chain 5; ND5
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17721, 26202, 4540
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P03915, P03921, P11661
• Gene Symbols: MT-ND5, ND5
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of mouse MT-ND5 (NP_9043381).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG