MT1-MMP Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9537	150 μL

Catalog No. 50-172-9537 Supplier Proteintech Group Inc Supplier No. 145521AP150UL

Description

Rabbit Polyclonal Antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Specifications

• Antigen: MT1-MMP
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: MMP14
• Gene Accession No.: P50281, P53690, Q10739
• Gene Alias: Matrix metalloproteinase 14, MMP 14, MMP X1, MMP14, MT MMP 1, MT1 MMP, MT1MMP, MT1-MMP, MTMMP1
• Gene Symbols: Mmp14, mmp14a
• Host Species: Rabbit
• Immunogen: MT1-MMP Fusion Protein Ag5965
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17387, 373882, 4323, 81707
• Target Species: Human, Mouse, Rat, Zebrafish
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG