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Invitrogen™ MT1 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5121779
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100 μL
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PIPA5121779 20 μL
PIPA5121778 100 μL
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Catalog No. PIPA5121779 Supplier Invitrogen™ Supplier No. PA5121779
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Description

Rabbit Polyclonal Antibody

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene MT1A
Gene Accession No. P04731
Gene Alias Metallothionein; Metallothionein-1
Gene Symbols MT1A
Host Species Rabbit
Immunogen Met1-Ala61 (Accession P04731), with N-terminal His Tag.
Purification Method Antigen affinity chromatography, Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4489
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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