Invitrogen™ MT3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552042

Catalog No. PIPA552042

Description

Immunogen sequence: MDPETCPCPS GGSCTCADSC KCEGCKCTSC KKSCCSCCPA ECEKCAKDCV CKGGEAAEAE AEKCS Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 83%.

Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease.

Specifications

• Antigen: MT3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MT3
• Gene Alias: GIF; GIFB; GRIF; growth inhibitory factor; metallothionein 3; metallothionein 3 (growth inhibitory factor (neurotrophic)); metallothionein III; metallothionein-3; Metallothionein-III; MT3; MT-3; MT-III; ZnMT3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4504
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P25713
• Gene Symbols: MT3
• Immunogen: Recombinant protein corresponding to Human MT3. Recombinant protein control fragment (Product #RP-102274).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG