MT3 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550448
The antibody detects endogenous levels of total MT3 protein.Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease.
|Full length fusion protein of Human MT3|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|GIF, GIFB, GRIF, ZnMT3|
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