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MT3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550448

Catalog No. PA550448


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Description

Description

The antibody detects endogenous levels of total MT3 protein.

Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease.
Specifications

Specifications

MT3
Polyclonal
Unconjugated
MT3
Liquid
MT3
Full length fusion protein of Human MT3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
2.1 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P25713
GIF, GIFB, GRIF, ZnMT3
Rabbit
IgG
100 μL
-20°C
Primary
4504
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