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MTA1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501571352
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50-157-1352 10 μL
50-157-1351 100 μL
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Catalog No. 50-157-1352 Supplier Bethyl Laboratories, Inc Supplier No. IHC00026T
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Horse, Panda, Orangutan, Monkey, Gorilla, Northern white-cheeked gibbon, African ele

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.

Specifications

Antigen MTA1
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MTA1
Gene Accession No. Q13330
Gene Alias metastasis associated gene 1 protein
Gene Symbols MTA1
Host Species Rabbit
Immunogen Between 400 and 450
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9112
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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