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Invitrogen™ MTBP Polyclonal Antibody
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Catalog No. PIPA530522
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100 μL
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Catalog No. Quantity
PIPA530522 100 μL
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Catalog No. PIPA530522 Supplier Invitrogen™ Supplier No. PA530522
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Jurkat, THP-1, HL-60. Predicted reactivity: Mouse (81%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTBP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Mtbp
Gene Accession No. Q96DY7
Gene Alias AI429604; hdm2; HDMX; hMTBP; MDM2 (mouse double minute 2)-binding protein, 104kD; MDM2 binding protein; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa; Mdm2, transformed 3T3 cell double minute p53 binding protein; mdm2-binding protein; MDM2BP; MGC5370; MGC71221; mMTBP; Mtbp; RGD1565672
Gene Symbols Mtbp
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MTBP. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27085
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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