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Invitrogen™ MTBP Polyclonal Antibody
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Catalog No. PIPA5110909
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100 μL
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PIPA5110909 100 μL
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Catalog No. PIPA5110909 Supplier Invitrogen™ Supplier No. PA5110909
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DAKELLKYFT SDGLPIGDLQ PLPIQKGEKT FVLTPELSPG KLQVLPFEKA SVCHYHGIEY CLDDRKALER DGGFSELQSR LIRYETQTTC TR Highest antigen sequence indentity to the following orthologs: Rat - 91%, Mouse - 93%.

MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTBP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mtbp
Gene Accession No. Q96DY7
Gene Alias AI429604; hdm2; HDMX; hMTBP; MDM2 (mouse double minute 2)-binding protein, 104kD; MDM2 binding protein; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa; Mdm2, transformed 3T3 cell double minute p53 binding protein; mdm2-binding protein; MDM2BP; MGC5370; MGC71221; mMTBP; Mtbp; RGD1565672
Gene Symbols Mtbp
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human MTBP. Recombinant protein control fragment (Product #RP-93903).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27085
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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