Invitrogen™ MTCH2 Polyclonal Antibody

Catalog No.	Quantity
PIPA520696	100 μg

Catalog No. PIPA520696 Supplier Invitrogen™ Supplier No. PA520696

Description

Rabbit Polyclonal Antibody

A suggested positive control is 293 cell lysate. PA5-20696 can be used with blocking peptide PEP-0811.

MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.

Specifications

• Antigen: MTCH2
• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% sodium azide
• Gene: Mtch2
• Gene Accession No.: Q791V5, Q9Y6C9
• Gene Alias: 2310034D24Rik; 4930539J07Rik; HSPC032; Met-induced mitochondrial protein; MIMP; mitochondrial carrier 2; mitochondrial carrier homolog 2; mitochondrial carrier homolog 2 (C. elegans); Mtch2; SLC25A50; solute carrier family 25, member 50
• Gene Symbols: Mtch2
• Host Species: Rabbit
• Immunogen: A 15 amino acid peptide near the amino terminus of human MTCH2.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23788, 56428
• Target Species: Human, Mouse
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG