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Invitrogen™ MTCH2 Polyclonal Antibody
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Catalog No. PIPA588873
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100 μL
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PIPA588873 100 μL
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Catalog No. PIPA588873 Supplier Invitrogen™ Supplier No. PA588873
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VGYEPLPPTI GRNIFGRQVC QLPGLFSYAQ HIASIDGRRG LFTGLTPRLC SGVLGTVVHG KVLQHYQESD KGEELGPGNV QKEVSSSFDH VIKETTREMI ARSAATLITH PFHVITLRSM VQFIGRESKY CGLCDSIITI YREEGI; Positive Samples: HepG2, HeLa, 293T, HT-29, Mouse small intestine, Mouse brain, Mouse liver; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein.

MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTCH2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Mtch2
Gene Accession No. Q791V5, Q9Y6C9
Gene Alias 2310034D24Rik; 4930539J07Rik; HSPC032; Met-induced mitochondrial protein; MIMP; mitochondrial carrier 2; mitochondrial carrier homolog 2; mitochondrial carrier homolog 2 (C. elegans); Mtch2; SLC25A50; solute carrier family 25, member 50
Gene Symbols Mtch2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-175 of human MTCH2 (NP_0551571).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23788, 56428
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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