Invitrogen™ MTERFD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597246

Catalog No. PIPA597246

Description

Immunogen sequence: SSQSTSSSSQ ENNSAQSSLL PSMNEQSQKT QNISSFDSEL FLEELDELPP LSPMQPISEE EAIQIIADPP LPPASFTLRD YVDHSETLQK LVLLGVDLSK IEKHPEAANL LLRLDFEKDI KQMLLFLKDV GIEDNQLGAF LTKNHAIFSE DLENLKTRVA YLHSKNFSKA DVAQMVRKAP FLLNFSVERL DNRLGFFQKE LELSVKKTRD LVVRLPRLLT GSLEPVKENM KV; Positive Samples: HepG2, 293T, SH-SY5Y, NCI-H460, SKOV3, BT-474; Cellular Location: Mitochondrion.

Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD1 is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It binds promoter DNA and acts as a mitochondrial transcription regulator. It has been suggested that only the phosphorylated form of MTERFD1 has transcription termination activity. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.

Specifications

• Antigen: MTERFD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTERF3
• Gene Alias: 2410017I18Rik; Cgi12; CGI-12; Mitochondrial transcription termination factor 3; MTERF domain containing 1; mTERF domain-containing protein 1, mitochondrial; Mterf3; MTERFD1; transcription termination factor 3, mitochondrial
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51001, 66410
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.35 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8R3J4, Q96E29
• Gene Symbols: MTERF3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 69-300 of human MTERFD1 (NP_0570263).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG