Invitrogen™ MTG16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589998

Catalog No. PIPA589998

Description

Positive Samples: K-562, U-251MG; Cellular Location: Golgi apparatus membrane, Nucleus, nucleolus, nucleoplasm Immunogen sequence: GQSLQGPTAV VADPVPGPPE AAHSLGPSLP VGAASPSEAG SAGPSRPGSP SPPGPLDTVP R.

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Specifications

• Antigen: MTG16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CBFA2T3
• Gene Alias: A630044F12Rik; AI465270; AW229127; CBFA2/RUNX1 partner transcriptional co-repressor 3; CBFA2/RUNX1 translocation partner 3; CBFA2T3; Cbfa2t3h; core-binding factor, runt domain, alpha subunit 2, translocated to, 3; core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human); core-binding factor, runt domain, alpha subunit 2; translocated to, 3; eight twenty one protein 2; ETO/MTG8-related protein ETO-2; Eto2; ETO-2; hMTG16; MTG16; MTG16HEL; MTG8-related gene 2; MTG8-related protein 2; MTGR2; myeloid translocation gene 8 and 16b; myeloid translocation gene on chromosome 16 protein; myeloid translocation gene-related protein 2; protein CBFA2T3; Protein ETO-2; RUNX1T3; translocated to, 3; zinc finger MYND domain-containing protein 4; ZMYND4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12398, 361431, 863
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.85 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O54972, O75081
• Gene Symbols: CBFA2T3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 593-653 of human CBFA2T3 (NP_0051784).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG