Invitrogen™ MTHFD1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518923

Catalog No. PIPA518923

Description

This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

Specifications

• Antigen: MTHFD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTHFD1
• Gene Alias: 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase; C1-tetrahydrofolate synthase; C-1-tetrahydrofolate synthase, cytoplasmic; C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed; C1-THF synthase; cytoplasmic C-1-tetrahydrofolate synthase; Dcs; E430024A07Rik; Formyltetrahydrofolate synthetase; LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic; methenyltetrahydrofolate; methenyltetrahydrofolate cyclohydrolase; Methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase; methylenetetrahydrofolate dehydrogenase 1; methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1; MTHFC; MTHFD; MTHFD1; MTHFD1 protein; formyltetrahydrofolate synthetase; methenyltetrahydrofolate cyclohydrolase,
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 4522
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P11586
• Gene Symbols: MTHFD1
• Immunogen: Synthetic peptide sequence (RGDLNDCFIPCTPK) corresponding to the internal amino acids of MTHFD1 (aa 137-151).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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