Invitrogen™ MTHFD1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596880

Catalog No. PIPA596880

Description

Immunogen sequence: GVPLKKEYTE ENIQLVADGC CNLQKQIQIT QLFGVPVVVA LNVFKTDTRA EIDLVCELAK RAGAFDAVPC YHWSVGGKGS VDLARAVREA ASKRSRFQFL YDVQVPIVDK IRTIAQAVYG AKDIELSPEA QAKIDRYTQQ GFGNLPICMA KTHLSLSHQP DKKGVPRDFI LPISDVRASI GAGFIYPLVG TMSTMPGLPT RPCFYDIDLD TETEQVKGLF; Positive Samples: A-549, placenta, Mouse brain, Mouse heart, Rat brain; Cellular Location: Mitochondrion.

One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).

Specifications

• Antigen: MTHFD1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTHFD1L
• Gene Alias: 10-formyl-THF synthetase; 2410004L15Rik; AI647056; dJ292B18.2; Formyltetrahydrofolate synthetase; formyltetrahydrofolate synthetase domain containing 1; FTHFSDC1; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; monofunctional C1-tetrahydrofolate synthase, mitochondrial; MTC1THFS; MTHFD1L
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25902, 270685, 361472
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 3.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q3V3R1, Q6UB35
• Gene Symbols: MTHFD1L
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 759-978 of human MTHFD1L (NP_0562552).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG