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Invitrogen™ MTHFR Monoclonal Antibody (5D3)
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Catalog No. PIMA515844
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100 μL
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Catalog No. Quantity
PIMA515844 100 μL
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Catalog No. PIMA515844 Supplier Invitrogen™ Supplier No. MA515844
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Description

Mouse Monoclonal Antibody

MA5-15844 targets MTHFR in indirect ELISA, IHC and WB applications and shows reactivity with Human and Rat samples. The MA5-15844 immunogen is purified recombinant fragment of human MTHFR expressed in E. Coli. . MA5-15844 detects MTHFR which has a predicted molecular weight of approximately 75kDa.

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTHFR
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 5D3
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene MTHFR
Gene Accession No. P42898
Gene Alias 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); AI323986; Methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H); MTHFR; RP11-56N19.4
Gene Symbols MTHFR
Host Species Mouse
Immunogen Purified recombinant fragment of human MTHFR expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 362657, 4524
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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