Invitrogen™ MTHFR Monoclonal Antibody (5D3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515844

Catalog No. PIMA515844

Description

MA5-15844 targets MTHFR in indirect ELISA, IHC and WB applications and shows reactivity with Human and Rat samples. The MA5-15844 immunogen is purified recombinant fragment of human MTHFR expressed in E. Coli. . MA5-15844 detects MTHFR which has a predicted molecular weight of approximately 75kDa.

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Specifications

• Antigen: MTHFR
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P42898
• Gene Symbols: MTHFR
• Immunogen: Purified recombinant fragment of human MTHFR expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 362657, 4524
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5D3
• Conjugate: Unconjugated
• Gene: MTHFR
• Gene Alias: 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); AI323986; Methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H); MTHFR; RP11-56N19.4
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1