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Invitrogen™ MTHFR Polyclonal Antibody
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Catalog No. PIPA5140282
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100 μL
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PIPA5140282 100 μL
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Catalog No. PIPA5140282 Supplier Invitrogen™ Supplier No. PA5140282
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: EELTSEESVF EVFVLYLSGE PNRNGHKVTC LPWNDEPLAA ETSLLKEELL RVNRQGILTI NSQPNINGKP SSDPI Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 88%.

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTHFR
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MTHFR
Gene Accession No. P42898
Gene Alias 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); AI323986; Methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H); MTHFR; RP11-56N19.4
Gene Symbols MTHFR
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MTHFR. Recombinant protein control fragment (Product #RP-109540).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4524
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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