Invitrogen™ MTHFR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140293

Catalog No. PIPA5140293

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: TILHMTCCRQ RLEEITGHLH KAKQLGLKNI MALRGDPIGD QWEEEEGGFN YAVDLVKHIR SEFGDYFDIC VAGYPKGHPE AGS.

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Specifications

• Antigen: MTHFR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTHFR
• Gene Alias: 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); AI323986; Methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H); MTHFR; RP11-56N19.4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4524
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P42898
• Gene Symbols: MTHFR
• Immunogen: Recombinant protein corresponding to Human MTHFR. Recombinant protein control fragment (Product #RP-109622).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG