MTLC Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0219	100 μL

Catalog No. 50-198-0219 Supplier Bioss Supplier No. BS0334R

Description

Rabbit Polyclonal Antibody

MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.

Specifications

• Antigen: MTLC
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Myct1
• Gene Accession No.: Q8N699
• Gene Alias: 1110020B04Rik; AI225941; AI642973; MTLC; Mtmc1; MT-MC1; myc target 1; myc target in myeloid cells 1; Myc target in myeloid cells protein 1; Myc target protein 1; MYCT1
• Gene Symbols: Myct1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human MTLC.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 80177
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG