Invitrogen™ MTMR4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120350

Catalog No. PIPA5120350

Description

Positive test controls include: 293T, HepG2, Mouse brain, Mouse liver. The target is usually found in the following locations: Cytoplasm, Membrane, Peripheral membrane protein. Immunogen sequence: GEATPRRLLS YGCCSKRPNS KQMRATGPCF GGQWAQREGV KSPVCSSHSN GHCTGPGGKN QMWLSSHPKQ VSSTKPVPLN CPSPVPPLYL DDDGLPFPTD VIQHRLRQIE AGYKQEVEQL RRQVRELQMR LDIRHCCAPP AEPPMDYEDD FTCLKESDGS DTEDFGSDHS EDCLSEASWE PVDKKETEVT RWVPDHMASH CYNCDCEFWL AKRRHHCRNC GNVFCAGCCH LKLPIPDQQL YDPVLVCNSC YEHIQVSRAR ELMSQQLKKP IATASS.

MTMR, a member of the myotubularin family, encodes an intracellular protein of 1, 195 amino acids, and shares approximately 47% sequence identity with MTMR3, spiking to over 70% identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.

Specifications

• Antigen: MTMR4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTMR4
• Gene Alias: AA596759; DKFZp781E194; ESTM44; FYVE domain-containing dual specificity protein phosphatase 2; FYVE zinc finger phosphatase; FYVE-DSP2; KIAA0647; MGC163449; MGC163451; mKIAA0647; Mtmr4; MTMR7; myotubularin related protein 4; myotubularin-related protein 4; ZFYVE11; Zinc finger FYVE domain-containing protein 11; zinc finger, FYVE domain containing 11
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170749, 287607, 9110
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q91XS1, Q9NYA4
• Gene Symbols: MTMR4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 920-1195 of human MTMR4 (NP_004678.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG