Invitrogen™ MTNR1A Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA519109

Catalog No. PIPA519109

Description

This antibody is predicted to react with bovine, canine and mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Specifications

• Antigen: MTNR1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTNR1A
• Gene Alias: mel1a melatonin receptor; mel1a receptor; Mel-1A-R; melatonin receptor 1A; melatonin receptor type 1A; MelR; MR; MT1; Mtnr1a
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 114211
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P49218
• Gene Symbols: MTNR1A
• Immunogen: Synthetic peptide sequence (SLKYDKLYSSKNS) corresponding to the internal amino acids of MTNR1A (aa 132-144).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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