Invitrogen™ MTNR1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550522

Catalog No. PA550522

Description

The antibody detects endogenous levels of total MTNR1A protein.

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Specifications

• Antigen: MTNR1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTNR1A
• Gene Alias: mel1a melatonin receptor; mel1a receptor; Mel-1A-R; melatonin receptor 1A; melatonin receptor type 1A; MelR; MR; MT1; Mtnr1a
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17773, 4543
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P48039, Q61184
• Gene Symbols: MTNR1A
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human melatonin receptor 1A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG