Invitrogen™ MTNR1A Polyclonal Antibody

Catalog No.	Quantity
PA550522	100 μL

Catalog No. PA550522 Supplier Invitrogen™ Supplier No. PA550522

Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total MTNR1A protein.

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Specifications

• Antigen: MTNR1A
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: MTNR1A
• Gene Accession No.: P48039, Q61184
• Gene Alias: mel1a melatonin receptor; mel1a receptor; Mel-1A-R; melatonin receptor 1A; melatonin receptor type 1A; MelR; MR; MT1; Mtnr1a
• Gene Symbols: MTNR1A
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human melatonin receptor 1A.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17773, 4543
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG