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mTOR Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501557776
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50-155-7776 100 μL
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Catalog No. 50-155-7776 Supplier Bethyl Laboratories, Inc Supplier No. A300503A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.

Specifications

Antigen mTOR
Applications Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene MTOR
Gene Accession No. P42345
Gene Alias MTOR, m-TOR, Mechanistic Target Of Rapamycin, Mammalian Target Of Rapamycin, FRAP, FRAP1, FRAP2, FK506 binding protein 12-rapamycin associated protein, FKBP-Rapamycin Associated Protein, Rapamycin Target Protein, Serine/Threonine-Protein Kinase MTOR, EC 2.7.11.1, RAFT1, RAPT1, mTORC1
Gene Symbols MTOR
Host Species Rabbit
Immunogen Between 200 and 250
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2475
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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