mTOR Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300503A

Catalog No. 50-155-7776

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.

Specifications

• Antigen: mTOR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTOR
• Gene Alias: MTOR, m-TOR, Mechanistic Target Of Rapamycin, Mammalian Target Of Rapamycin, FRAP, FRAP1, FRAP2, FK506 binding protein 12-rapamycin associated protein, FKBP-Rapamycin Associated Protein, Rapamycin Target Protein, Serine/Threonine-Protein Kinase MTOR, EC 2.7.11.1, RAFT1, RAPT1, mTORC1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2475
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: P42345
• Gene Symbols: MTOR
• Immunogen: Between 200 and 250
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG