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Invitrogen™ MTRR Polyclonal Antibody
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Catalog No. PIPA589941
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100 μL
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PIPA589941 100 μL
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Catalog No. PIPA589941 Supplier Invitrogen™ Supplier No. PA589941
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TAPLVVVVST TGTGDPPDTA RKFVKEIQNQ TLPVDFFAHL RYGLLGLGDS EYTYFCNGGK IIDKRLQELG ARHFYDTGHA DDCVGLELVV EPWIAGLWPA LRKHFRSSRG QEEISGALPV ASPASSRTDL VKSELLHIES QVELLRFDDS GRKDSEVLKQ NAVNSNQSNV VIEDFESSLT R; Positive Samples: A-549, HeLa, LO2, 293T; Cellular Location: Cytoplasm, Cytoplasm.

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTRR
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene MTRR
Gene Accession No. Q9UBK8
Gene Alias [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing); 4732420G08; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase; aqCbl reductase; aquacobalamin reductase; cblE; Methionine synthase reductase; methionine synthase reductase, mitochondrial; MGC129643; MSR; Mtrr
Gene Symbols MTRR
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human MTRR (NP_0024452).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4552
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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