Invitrogen™ MTRR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118094

Catalog No. PIPA5118094

Description

MTRR Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), IP

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: MTRR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTRR
• Gene Alias: [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing); 4732420G08; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase; aqCbl reductase; aquacobalamin reductase; cblE; Methionine synthase reductase; methionine synthase reductase, mitochondrial; MGC129643; MSR; Mtrr
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4552
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: Q9UBK8
• Gene Symbols: MTRR
• Immunogen: E. coli-derived Human MTRR fragment.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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