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MUC1 Antibody (VU-2G7), Alexa Fluor™ 594, Novus Biologicals™
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Catalog No. NP247882A94 Shop All R&D Systems Products
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NP247882A94 0.1 mL
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Catalog No. NP247882A94 Supplier Novus Biologicals Supplier No. NBP247882AF594
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Description

Mouse Monoclonal Antibody

MUC1 Monoclonal specifically detects MUC1 in Human samples. It is validated for ELISA.

Specifications

Antigen MUC1
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone VU-2G7
Conjugate Alexa Fluor 594
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Gene Symbols MUC1
Host Species Mouse
Immunogen Synthetic glycosylated MUC1 60mer tandem repeat NH2-(HGVTSAPDT(GalNAc)RPAPGSTAPPAHG)3- COOH, conjugated to bovine serum albumin (Uniprot: P15941)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 4582.0
Test Specificity monoclonal antibody VU-2G7 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of VU-2G7 has not been established with 'epitope fingerprinting'. The'extra cellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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