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MUC1 Mouse, Clone: 139H2, Abnova™

Catalog No. 89934609 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-934-609 50 μg
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Catalog No. 89-934-609 Supplier Abnova Corporation Supplier No. MAB12660

Description

Mouse monoclonal antibody raised against human MUC1.

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq]

Specifications

Antigen MUC1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 139H2
Conjugate Unconjugated
Formulation In PBS (0.05% sodium azide).
Gene Alias CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM
Gene Symbols MUC1
Host Species Mouse
Immunogen Deglycosylated purified MUC1 glycoprotein.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4582
Target Species Human
Content And Storage Store at 4°C. For long term storage store at −20°C. Aliquot to avoid repeated freezing and thawing.
Isotype IgG1
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