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MUC1 Mouse anti-Human, Clone: 175C5, Abnova™

Catalog No. 89934612 Shop All Abnova Corporation Products
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89-934-612 100 μL
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Catalog No. 89-934-612 Supplier Abnova Corporation Supplier No. MAB12714
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Description

Mouse monoclonal antibody raised against human MUC1.

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq]

Specifications

Antigen MUC1
Applications ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 175C5
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against human MUC1.
Dilution ELISA Flow Cytometry Immunofluorescence Immunohistochemistry (Frozen sections) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) Immunoprecipitation Western Blot The optimal working dilution should be determ
Formulation In tissue culture supernatant (0.09% sodium azide).
Gene Alias CD227/EMA/H23AG/MAM6/PEM/PEMT/PUM
Gene Symbols MUC1
Host Species Mouse
Immunogen Human mammary carcinoma cell line (ZR-75-1)
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4582
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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