Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MUC1 Mouse anti-Human, Clone: MUC1/967, Abnova™

Mouse monoclonal antibody raised against native human MUC1.

Manufacturer:  Abnova Corporation MAB13359

Catalog No. 89-934-603


Add to cart

Description

Description

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq]

Specifications

Specifications

MUC1
MUC1/967
Mouse monoclonal antibody raised against native human MUC1.
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
CD227/EMA/H23AG/MAM6/PEM/PEMT/PUM
Mouse
IgG1, kappa
100 ug
Store at 4°C.
Monoclonal
The dominant epitope of this monoclonal antibody is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine.
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Unconjugated
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
Liquid
MUC1
Human milk-fat globule membranes (HMFGM).
Protein A/G purification
RUO
Primary
4582
Human
SDS
Documents
Product Certifications
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit