Invitrogen™ MUC20 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590867

Catalog No. PIPA590867

Description

Immunogen sequence: PNFMVLIATS VETSAASGSP EGAGMTTVQT ITGSDPEEAI FDTLCTDDSS EEAKTLTMDI LTLAHTSTEA KGLSSESSAS SDGPHPVITP SRASESSASS D; Positive Samples: 293T, A-549, DU145, LO2, U-251MG, HT-29, Mouse kidney, Mouse lung, Rat kidney; Cellular Location: Apical cell membrane, Basolateral cell membrane, Cell projection, microvillus membrane.

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MUC20
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Muc20
• Gene Alias: BC026367; KIAA1359; Muc20; MUC-20; mucin 20; mucin 20, cell surface associated; mucin-20; transmembrane mucin MUC20S; UNQ2782/PRO7170
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 200958, 224116, 303886
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.06 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8BUE7, Q8N307
• Gene Symbols: Muc20
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MUC20 (NP_6898863).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG