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MUC5AC Antibody (1-13M1), Novus Biologicals™
SDP

Catalog No. p-5540928 Shop All R&D Systems Products
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NBP24445200 0.02 mg
NBP24445201 0.1 mg
NBP24445202 0.2 mg
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Catalog No. NBP24445200 Supplier Novus Biologicals Supplier No. NBP2444520.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence

MUC5AC Monoclonal specifically detects MUC5AC in Human, Mouse, Rat, Bovine, Chicken, Feline, Monkey, Rabbit, Porcine (Negative) samples. It is validated for ELISA.

Specifications

Antigen Mucin 5AC
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence
Classification Monoclonal
Clone 1-13M1
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
Gene Symbols MUC5AC
Host Species Mouse
Immunogen M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient.
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Extracellular Matrix
Primary or Secondary Primary
Gene ID (Entrez) 4586
Test Specificity This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. MAb 1-13M1 pairs with MAb 9-13M1 to measure MUC5AC protein by ELISA. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Target Species Human, Mouse, Rat, Chicken, Feline, Monkey, Rabbit, Porcine (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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