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MUC5AC Antibody (MUC5AC/917), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP24448A32 Shop All R&D Systems Products
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NP24448A32 0.1 mL
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Catalog No. NP24448A32 Supplier Novus Biologicals Supplier No. NBP254448AF532
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Description

Mouse Monoclonal Antibody

MUC5AC Monoclonal specifically detects MUC5AC in Human, Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen MUC5AC
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone MUC5AC/917
Conjugate Alexa Fluor 532
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
Gene Symbols MUC5AC
Host Species Mouse
Immunogen Recombinant fragment covering tandem repeats of human MUC5AC protein (exact sequence is proprietary) (Uniprot: P98088)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cellular Markers, Extracellular Matrix, Infections (Virus Bacteria and Parasites), Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 4586.0
Test Specificity Mucin 5AC glycoprotein (MUC5AC) is a 641kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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