MUC5AC Antibody (MUC5AC/917) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NB254448100	Novus Biologicals NBP254448100UG	100 μg
NB254448200	Novus Biologicals NBP254448200UG	200 μg

Description

MUC5AC Monoclonal specifically detects MUC5AC in Human, Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, CyTOF-ready.

Specifications

• Antigen: Mucin 5AC
• Concentration: 1 mg/mL
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Extracellular Matrix
• Formulation: PBS with No Preservative
• Gene ID (Entrez): 4586
• Immunogen: Recombinant human MUC5AC protein
• Primary or Secondary: Primary
• Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Molecular Weight of Antigen: 641 kDa

• Clone: MUC5AC/917
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Rat (Negative)
• Gene Alias: gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
• Gene Symbols: MUC5AC
• Isotype: IgG1 κ
• Purification Method: Protein A or G purified
• Test Specificity: Mucin 5AC glycoprotein (MUC5AC) is a 641kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

For Research Use Only