MUC5AC Antibody (SPM297), Alexa Fluor™ 532, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234758AF532

Catalog No. NB006572

Description

MUC5AC Monoclonal specifically detects MUC5AC in Human, Mouse, Rat, Porcine, Chicken, Feline, Mammal, Monkey, Rabbit, Bovine (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: MUC5AC
• Classification: Monoclonal
• Conjugate: Alexa Fluor 532
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: MUC5AC
• Immunogen: M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
• Quantity: 0.1 mL
• Research Discipline: Cellular Markers, Extracellular Matrix, Infections (Virus Bacteria and Parasites), Signal Transduction
• Test Specificity: This monoclonal antibody recognizes the peptide core of gastric mucin M1 (1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: SPM297
• Dilution: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Pig, Chicken, Feline, Monkey, Rabbit, Bovine (Negative)
• Isotype: IgG1 κ