Invitrogen™ MUC5AC Monoclonal Antibody (58M1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135707

Catalog No. 01-672-013

Description

58M1 recognizes the peptide core of gastric mucin M1 (now: MUC5AC), and more specifically with the e epitope amongst the a, b, c, d, e, f, g and h protein core epitopes defined by Bara for M1. MUC5AC is present in primary ovarian mucinous cancer and gastric cancer, but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

The antibody 2-25LE reacts with Lewisb blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.

Specifications

• Antigen: MUC5AC
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P98088
• Gene Symbols: MUC5AC
• Immunogen: Mucin isolated from an ovarian cyst fluid.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey, Bovine, Feline
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: 58M1
• Conjugate: Unconjugated
• Gene: MUC5AC
• Gene Alias: 2210005L13Rik; gastric mucin; LeB; lewis B blood group antigen; LOW QUALITY PROTEIN: mucin-5AC; major airway glycoprotein; MGM; MUC5; MUC5AC; MUC-5AC; mucin; mucin 5, subtypes A and C; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5ac; mucin 5AC, oligomeric mucus/gel-forming; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; Mucin-5AC; TBM; Tracheobronchial mucin
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 100847395, 105261014, 17833, 4586
• Content And Storage: 4°C
• Form: Liquid