Invitrogen™ MUC5B Monoclonal Antibody (C10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543650

Catalog No. PIMA543650

Description

MUC5B Monoclonal Antibody for Western Blot

Mucins (MUCs) are heavily glycosylated glycoproteins that are synthesized either as membrane-bound or secreted proteins. Mucins are noteworthy because they have an aberrant expression profile in various malignancies. Mucins normally play a protective role for epithelial tissues and are expressed in the gastrointestinal, respiratory, and genito-urinary tracts. Mucins may also be involved in the renewal and differentiation of the epithelium, and the modulation of cell adhesion and cell signaling. MUC5B is thought to play a vital role in maintaining oral health, and may also be involved in respiratory and oral disease.2 MUC5B expression has been studied in gastric carcinoma as well as chronic obstructive pulmonary disease.

Specifications

• Antigen: MUC5B
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q9HC84
• Gene Symbols: MUC5B
• Immunogen: Recombinant protein Mucin 5 Subtype B. The antigen corresponds to amino acid range 5653-5762 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Western Blot
• Clone: C10
• Conjugate: Unconjugated
• Gene: MUC5B
• Gene Alias: Cervical mucin; cervical mucin MUC5B; high molecular weight salivary mucin MG1; MG1; MUC5; MUC5B; MUC-5B; MUC9; mucin 5, subtype B, tracheobronchial; mucin 5B, oligomeric mucus/gel-forming; Mucin-5 subtype B, tracheobronchial; Mucin-5B; sublingual gland mucin
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 727897
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov