Invitrogen™ MUC5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103930

Catalog No. PIPA5103930

Description

Antibody detects endogenous levels of total MUC5B.

Mucins (MUCs) are heavily glycosylated glycoproteins that are synthesized either as membrane-bound or secreted proteins. Mucins are noteworthy because they have an aberrant expression profile in various malignancies. Mucins normally play a protective role for epithelial tissues and are expressed in the gastrointestinal, respiratory, and genito-urinary tracts. Mucins may also be involved in the renewal and differentiation of the epithelium, and the modulation of cell adhesion and cell signaling. MUC5B is thought to play a vital role in maintaining oral health, and may also be involved in respiratory and oral disease.2 MUC5B expression has been studied in gastric carcinoma as well as chronic obstructive pulmonary disease.

Specifications

• Antigen: MUC5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MUC5B
• Gene Alias: Cervical mucin; cervical mucin MUC5B; high molecular weight salivary mucin MG1; MG1; MUC5; MUC5B; MUC-5B; MUC9; mucin 5, subtype B, tracheobronchial; mucin 5B, oligomeric mucus/gel-forming; Mucin-5 subtype B, tracheobronchial; Mucin-5B; sublingual gland mucin
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 727897
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9HC84
• Gene Symbols: MUC5B
• Immunogen: A synthesized peptide derived from human MUC5B(Accession Q9HC84), corresponding to amino acid residues A2102-T2152.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov