Invitrogen™ MUL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100877

Catalog No. PIPA5100877

Description

Antibody detects endogenous levels of total MUL1.

E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Specifications

• Antigen: MUL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MUL1
• Gene Alias: 0610009K11Rik; AV000801; C1orf166; E3 SUMO-protein ligase MUL1; E3 ubiquitin ligase; E3 ubiquitin-protein ligase MUL1; Gide; growth inhibition and death E3 ligase; MAPL; mitochondria-anchored protein ligase; mitochondrial E3 ubiquitin ligase 1; mitochondrial E3 ubiquitin protein ligase 1; mitochondrial ubiquitin ligase activator of NF-kB; mitochondrial ubiquitin ligase activator of NFKB 1; Mitochondrial-anchored protein ligase; MUL1; MULAN; Putative NF-kappa-B-activating protein 266; RGD1309944; ring finger protein 218; RING-type E3 ubiquitin transferase NFKB 1; RNF218; RP11-401M16.2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 298576, 68350, 79594
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8VCM5, Q969V5
• Gene Symbols: MUL1
• Immunogen: A synthesized peptide derived from human MUL1(Accession Q969V5), corresponding to amino acid residues V191-K241.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov