MUPP1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A302878AT

Catalog No. 50-156-3714

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor1, and was found to co-localize with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus. MUPP1 contains 13 PDZ domains but no apparent catalytic domain. MUPP1 is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM). MUPP1 may therefore function as a multivalent scaffold protein that recruits various proteins to tight junctions. MUPP1 also interacts with claudin-8 and may play a role in tight junction barrier function.

Specifications

• Antigen: MUPP1
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: O75970
• Gene Symbols: MPDZ
• Immunogen: Between 1125 and 1150
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: MPDZ
• Gene Alias: Multiple PDZ domain protein, Multi-PDZ domain protein 1, Mpdz
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8777
• Content And Storage: 4° C
• Form: Liquid