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MUPP1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501563714
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50-156-3714 20 μL
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Catalog No. 50-156-3714 Supplier Bethyl Laboratories, Inc Supplier No. A302878AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor1, and was found to co-localize with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus. MUPP1 contains 13 PDZ domains but no apparent catalytic domain. MUPP1 is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM). MUPP1 may therefore function as a multivalent scaffold protein that recruits various proteins to tight junctions. MUPP1 also interacts with claudin-8 and may play a role in tight junction barrier function.

Specifications

Antigen MUPP1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MPDZ
Gene Accession No. O75970
Gene Alias Multiple PDZ domain protein, Multi-PDZ domain protein 1, Mpdz
Gene Symbols MPDZ
Host Species Rabbit
Immunogen Between 1125 and 1150
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8777
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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