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Invitrogen™ Muromonab Chimeric Recombinant Rabbit Monoclonal Antibody (OKT-3 (muromonab))
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA547769
Description
Specificity: Epitope on the epsilon-subunit within the human CD3 complex.
Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.
Specifications
Muromonab Chimeric | |
Recombinant Monoclonal | |
1 mg/mL | |
PBS with 0.02% ProClin 300 | |
P04235, P11942, P22646, P24161 | |
Human peripheral E+ cells. | |
200 μg | |
Primary | |
Human | |
Antibody | |
IgG κ |
Flow Cytometry, Immunocytochemistry | |
OKT-3 (muromonab) | |
Unconjugated | |
Cd247 | |
Rabbit | |
Protein A | |
RUO | |
12500, 12501, 12502, 12503 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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