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Invitrogen™ Muromonab Chimeric Recombinant Rabbit Monoclonal Antibody (OKT-3 (muromonab))
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Catalog No. PIMA547769
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200 μg
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Catalog No. Quantity
PIMA547769 200 μg
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Catalog No. PIMA547769 Supplier Invitrogen™ Supplier No. MA547769
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: Epitope on the epsilon-subunit within the human CD3 complex.

Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.
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Specifications

Antigen Muromonab Chimeric
Applications Flow Cytometry, Immunocytochemistry
Classification Recombinant Monoclonal
Clone OKT-3 (muromonab)
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Cd247
Gene Accession No. P04235, P11942, P22646, P24161
Host Species Rabbit
Immunogen Human peripheral E+ cells.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12500, 12501, 12502, 12503
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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