Invitrogen™ MUS81 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563743

Catalog No. PIPA563743

Description

Immunogen sequence: LVEEHGSVHN LSLPESTLLQ AVTNTQVIDG FFVKRTADIK ESAAYLALLT RGLQRLYQGH TLRSRPWGTP GNPESGAMTS PNPLCSLLTF SDFNAGAIKN KAQSVREVFA RQLMQVRGVS GEKAAALVDR YSTPA Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

Specifications

• Antigen: MUS81
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MUS81
• Gene Alias: 1200008A18Rik; AI182501; AW045863; crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81; MUS81 endonuclease homolog; MUS81 endonuclease homolog (yeast); MUS81 structure-specific endonuclease subunit; SLX3; SLX3 structure-specific endonuclease subunit homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80198
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96NY9
• Gene Symbols: MUS81
• Immunogen: Recombinant protein corresponding to Human MUS81. Recombinant protein control fragment (Product # RP-89866).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG