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Invitrogen™ MUS81 Polyclonal Antibody
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Catalog No. PIPA5117071
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100 μL
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PIPA5117071 100 μL
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Catalog No. PIPA5117071 Supplier Invitrogen™ Supplier No. PA5117071
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Description

Rabbit Polyclonal Antibody

Positive Samples: HeLa, Jurkat Immunogen sequence: MAAPVRLGRK RPLPACPNPL FVRWLTEWRD EATRSRRRTR FVFQKALRSL RRYPLPLRSG KEAKILQHFG DGLCRMLDER LQRHRTSGGD HAPDSPSGEN SPAPQGRLAE VQDSSMPVPA QPKAGGSGSY WPARHSGARV ILLVLYREHL NPNGHHFLTK EELLQRCAQK SPRVAPGSAR PWPALRSLLH RNLVLRTHQP ARYSLTPEGL ELAQKLAESE GLSLLNVGIG PKEPPGEETA VPGAASAELA SEAGVQQQPL ELRPGEYRVL LCVDIGETRG GGHRPELLRE LQRLHVTHTV RKLHVGDFVW VAQETNPRDP ANPGELVLDH IVERKRLDDL CSSIIDGRFR.

Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MUS81
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene MUS81
Gene Accession No. Q4KM32, Q91ZJ0, Q96NY9
Gene Alias 1200008A18Rik; AI182501; AW045863; crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81; MUS81 endonuclease homolog; MUS81 endonuclease homolog (yeast); MUS81 structure-specific endonuclease subunit; SLX3; SLX3 structure-specific endonuclease subunit homolog
Gene Symbols MUS81
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MUS81 (NP_0794043).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 293678, 71711, 80198
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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