Invitrogen™ MUS81 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117071

Catalog No. PIPA5117071

Description

Positive Samples: HeLa, Jurkat Immunogen sequence: MAAPVRLGRK RPLPACPNPL FVRWLTEWRD EATRSRRRTR FVFQKALRSL RRYPLPLRSG KEAKILQHFG DGLCRMLDER LQRHRTSGGD HAPDSPSGEN SPAPQGRLAE VQDSSMPVPA QPKAGGSGSY WPARHSGARV ILLVLYREHL NPNGHHFLTK EELLQRCAQK SPRVAPGSAR PWPALRSLLH RNLVLRTHQP ARYSLTPEGL ELAQKLAESE GLSLLNVGIG PKEPPGEETA VPGAASAELA SEAGVQQQPL ELRPGEYRVL LCVDIGETRG GGHRPELLRE LQRLHVTHTV RKLHVGDFVW VAQETNPRDP ANPGELVLDH IVERKRLDDL CSSIIDGRFR.

Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

Specifications

• Antigen: MUS81
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MUS81
• Gene Alias: 1200008A18Rik; AI182501; AW045863; crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81; MUS81 endonuclease homolog; MUS81 endonuclease homolog (yeast); MUS81 structure-specific endonuclease subunit; SLX3; SLX3 structure-specific endonuclease subunit homolog
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 293678, 71711, 80198
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q4KM32, Q91ZJ0, Q96NY9
• Gene Symbols: MUS81
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MUS81 (NP_0794043).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG