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Invitrogen™ MUSK Polyclonal Antibody
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Catalog No. PIPA596178
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100 μL
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PIPA596178 100 μL
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Catalog No. PIPA596178 Supplier Invitrogen™ Supplier No. PA596178
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LTITTLYCCR RRKQWKNKKR ESAAVTLTTL PSELLLDRLH PNPMYQRMPL LLNPKLLSLE YPRNNIEYVR DIGEGAFGRV FQARAPGLLP YEPFTMVAVK MLKEEASADM QADFQREAAL MAEFDNPNIV KLLGVCAVGK PMCLLFEYMA YGDLNEFLRS MSPHTVCSLS HSDLSMRAQV SSPGPPPLSC AEQLCIARQV AAGMAYLSER KFVHRDLATR NCLVGENMVV KIADFGLSRN IYSADYYKAN ENDAIPIRWM PPESIFYNRY TTESDVWAYG VVLWEIFSYG LQPYYGMAHE EVIYYVRDGN ILSCPENCPV ELYNLMRLCW SKLPADRPSF TSIHRILERM CERAEGTVSV; Positive Samples: SW480; Cellular Location: Cell junction, Single-pass type I membrane protein, postsynaptic cell membrane, synapse.

MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn. Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells. Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor. MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MUSK
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4.01 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MUSK
Gene Accession No. Q61006
Gene Alias CMS9; FADS; Mdk4; MGC126323; MGC126324; Mlk; muscle associated receptor tyrosine kinase; muscle localized kinase 2; muscle specific kinase (neural fold/somite kinase 1); muscle, skeletal receptor tyrosine protein kinase; Muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific protein kinase secretory isoform; muscle-specific tyrosine kinase receptor MuSK; muscle-specific tyrosine protein kinase receptor; Muscle-specific tyrosine-protein kinase receptor; MuSK; Nsk1; Nsk2; Nsk3; RP23-170A3.1
Gene Symbols MUSK
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 424-783 of human MUSK (NP_0011597521).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18198
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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