MVK Monoclonal Antibody (OTI 1D7), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA502934

Catalog No. 50-167-3930

Description

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.

Specifications

• Antigen: MVK
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q03426
• Gene Symbols: MVK
• Immunogen: Full length human recombit protein of human MVK produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI 1D7
• Conjugate: Unconjugated
• Gene: MVK
• Gene Alias: LRBP, MK, MVLK, POROK3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4598
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid